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In group 1, the cumulative rate of rupture of aneurysms that were less than 10 mm in diameter at diagnosis was less than 0.005% per year, and in group 2, the rate was approximately 11 times as high (0.5% per year). the rupture rate of aneurysms that were 10 mm or more in diameter was less than 1% per year in both groups, but in group 1, the rate was 6% the first year for giant aneurysms (>/=25 mm in diameter). The size and location of the aneurysm were independent predictors of rupture. The overall rate of surgery-related morbidity and mortality was 17.5% in group 1 and 13.6% in group 2 at 30 days and was 15.7% and 13.1% respectively at 1 year. Age independently predicted surgical outcome. The likelihood of rupture of unruptured intracranial aneurysm that were less than 10 mm in diameter was exceedingly low among patients in group 1 and was substantially higher among those in group 2. The risk of morbidity and mortality related to surgery greatly exceeded the 7.5 year risk of rupture along patients in group 1 with unruptured intracranial aneurysms smaller than 10 mm in diameter. |
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